Highly drug-resistant gonorrhoea is spreading in the north of England with an outbreak centred in Leeds. The strain in this outbreak is highly resistant to antibiotic azithromycin, which is normally used alongside another antibiotic, ceftriaxone. There are very limited alternatives to treatment of gonorrhoea once resistance to azithromycin and ceftriaxone become widespread. Without treatment, the infection can lead to serious long-term health problems, including infertility, or potentially life-threatening pelvic inflammatory disease in women. In pregnant women it can also cause permanent blindness in a newborn. Read more.